Which comma-shaped bacterium did Robert Koch identify as a plague agent in 1883?
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Vibrio cholerae
It colonises the small intestine and releases a toxin.
💡 Did you know? Robert Koch described it more precisely in 1884.
15 questions · History
Cholera is a feared diarrhoeal disease that can kill a healthy person within hours. It is caused by the bacterium Vibrio cholerae, spread mainly through contaminated drinking water and food. In the 19th century cholera moved in several pandemics from its home in the Indian Ganges delta across the whole world and killed millions. The disease triggers massive, watery diarrhoea: sufferers lose so much fluid that they literally dry out; the skin turns bluish, the eyes sink in. For a long time people believed „bad air“ (miasma) was the cause. Only in 1854 did the London doctor John Snow prove that a contaminated water pump was the source of an outbreak: a milestone of modern epidemiology. Shortly after, Robert Koch identified the pathogen. The decisive weapon against cholera is still clean drinking water and working sewers; where these are lacking, it breaks out again and again. The simple, ingenious treatment is oral rehydration: a solution of water, salt and sugar that replaces the lost fluid and has saved millions of lives.
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Vibrio cholerae
It colonises the small intestine and releases a toxin.
💡 Did you know? Robert Koch described it more precisely in 1884.
Contaminated drinking water
Contaminated food also transmits it.
💡 Did you know? Clean sewage systems are the best protection.
Watery diarrhoea
It looks like „rice water“.
💡 Did you know? The body loses enormous amounts of fluid.
Dehydration
The massive fluid loss makes the circulation fail.
💡 Did you know? Untreated this can be fatal within hours.
Oral rehydration
A solution of water, salt and sugar.
💡 Did you know? It is seen as one of medicine's most important inventions.
John Snow
He had the handle of the Broad Street pump removed.
💡 Did you know? He is seen as a founder of modern epidemiology.
Robert Koch
The German bacteriologist found it in India in 1884.
💡 Did you know? Koch decisively shaped modern microbiology.
The Ganges delta (India)
From there it broke out worldwide in the 19th century.
💡 Did you know? Seven great cholera pandemics are known.
The miasma theory
People believed „bad air“ caused illness.
💡 Did you know? John Snow's work disproved this idea.
A working sewage system
Separating drinking and waste water is decisive.
💡 Did you know? Building modern sewers ended many outbreaks.
Yes
Especially after disasters and in war zones.
💡 Did you know? Mostly where clean water is lacking.
Bluish
That is why it was once called „blue cholera“.
💡 Did you know? The cause is extreme fluid loss.
Yes
Oral vaccines offer temporary protection.
💡 Did you know? Clean water still remains the key measure.
Pyotr Tchaikovsky
He is said to have drunk unboiled water.
💡 Did you know? The circumstances of his death are still disputed.
Epidemiology
It studies how diseases spread.
💡 Did you know? John Snow's map of deaths was its first tool.
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