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Smallpox

13 questions · History

Smallpox is one of the deadliest diseases in human history and at the same time the only one humankind has ever completely eradicated. It was caused by the variola virus, which jumped from person to person by droplets. The disease covered the body with pus-filled pustules; about one third of the sick died, survivors often bore disfiguring scars or went blind. For thousands of years smallpox claimed countless victims and changed the course of history, for instance when introduced pathogens wiped out much of the indigenous population of the Americas. The turning point came in 1796 with the English country doctor Edward Jenner: he observed that milkmaids infected with harmless cowpox were immune to real smallpox. From the Latin word for cow, „vacca“, came the term „vaccination“. Jenner's discovery was the birth of immunisation. More than a century and a half later the World Health Organization launched a worldwide vaccination campaign. In 1980 the WHO officially declared smallpox eradicated; a unique triumph of medicine that shows what global cooperation can achieve.

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All questions with answers

Which virus caused smallpox?

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The variola virus

The name comes from Latin „varius“ (spotted).

💡 Did you know? It infected humans only.

Which unique distinction do smallpox hold in medical history?

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The only disease ever eradicated

The virus survives only in high-security labs.

💡 Did you know? A one-of-a-kind medical success.

Which English doctor developed the first vaccination in 1796?

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Edward Jenner

He used harmless cowpox for protection.

💡 Did you know? He is seen as the founder of vaccination.

From which animal does the word „vaccine“ come?

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From the cow

Latin „vacca“ means cow.

💡 Did you know? Jenner inoculated with cowpox.

In which year did the WHO declare smallpox eradicated?

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1980

The last natural case occurred in 1977.

💡 Did you know? It ended a scourge thousands of years old.

Which typical skin changes marked smallpox?

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Pus-filled pustules

They covered the whole body.

💡 Did you know? Survivors often kept deep scars.

Roughly what share of the infected died of smallpox?

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About one third

For some forms the death rate was even higher.

💡 Did you know? In the 20th century hundreds of millions died of it.

Which consequence did smallpox have for many survivors?

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Scars and blindness

The pockmarks stayed for life.

💡 Did you know? Smallpox was a common cause of blindness.

Which population did introduced smallpox decimate especially?

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The indigenous peoples of the Americas

They had no immunity to the pathogen.

💡 Did you know? Whole cultures collapsed as a result.

How did the smallpox virus spread from person to person?

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By droplets

Scabs and clothing could also transmit it.

💡 Did you know? This made it highly contagious.

Which risky forerunner of vaccination existed before Jenner?

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Variolation

A small amount of real smallpox material was transferred.

💡 Did you know? This was riskier than Jenner's method.

Which organisation ran the global eradication campaign?

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The WHO

It launched the programme in the 1960s.

💡 Did you know? Vaccination teams travelled to the remotest villages.

Does the smallpox virus still exist anywhere today?

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Only in a few high-security labs

Officially in the USA and Russia.

💡 Did you know? Whether it should be destroyed is disputed.

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