Which bacterium causes epidemic typhus?
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Rickettsia prowazekii
It lives and multiplies inside body cells.
💡 Did you know? It is named after two researchers who died of it.
10 questions · History
Typhus (epidemic or spotted fever) (not to be confused with typhoid, caused by salmonellae) is a dangerous bacterial disease inseparable from war, hunger and misery. It is caused by the bacterium Rickettsia prowazekii, spread by the body louse: the louse takes up the pathogen while feeding and excretes it in its faeces, which enter the skin through scratches. Because lice spread wherever many people live crammed together without hygiene, typhus raged above all in army camps, prisons, trenches and concentration camps: earning the grim names „camp fever“, „famine fever“ or „war plague“. Napoleon's Grande Armée lost more soldiers to typhus on the Russian campaign than to enemy weapons, and in the camps of the Second World War, such as Bergen-Belsen, countless people died of it. Typical are sudden high fever, severe headache, stupor and the namesake spotted rash. The Frenchman Charles Nicolle received the Nobel Prize for the insight that the louse is the carrier. Today typhus is easily treatable with antibiotics, and consistent hygiene and delousing prevent its spread.
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Rickettsia prowazekii
It lives and multiplies inside body cells.
💡 Did you know? It is named after two researchers who died of it.
The body louse
The pathogen is in the louse's faeces.
💡 Did you know? It enters the skin through scratches.
With typhoid fever
Typhoid, by contrast, is caused by salmonellae.
💡 Did you know? The similar names still cause confusion today.
In war and hardship
Crowding and poor hygiene favour the lice.
💡 Did you know? That is why it was called „camp“ or „war fever“.
A spotted rash
It spreads over the whole body.
💡 Did you know? High fever and stupor add to it.
Charles Nicolle
The Frenchman recognised the route of transmission in 1909.
💡 Did you know? This first allowed the disease to be fought directly.
Napoleon's Russian campaign
More soldiers died of disease than in battle.
💡 Did you know? This helped doom the Grande Armée.
With antibiotics
Doxycycline in particular works very well.
💡 Did you know? Treated early, mortality drops sharply.
Delousing and hygiene
Without lice the pathogen cannot spread.
💡 Did you know? Historically the insecticide DDT helped.
In concentration camps
Countless people died of it in Bergen-Belsen.
💡 Did you know? Anne Frank too fell victim to typhus there.
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